ToolTrust
D63/100
Smithery

opentargets

mcpsmithery

@Smithery

Explore drug-target associations and disease-gene evidence. Search targets, diseases, and drugs with genetics and literature-backed data.

By Smithery | 24 findings | Scanned 4/19/2026 | tooltrust-scanner/v0.3.8

10 High5 Medium4 Low5 Info

Risk Summary

Block in Production

Excessive Permissions + Dep Visibility risk is significant. Avoid using this in production agents.

Potential impact: The agent may gain overly broad access to files, network, databases, or execution capabilities.

Recommended action: This tool should stay disabled in production agents until the flagged risks are fixed and the scan is clean.

{
  "mcpServers": {
    "opentargets": {
      "disabled": true
    }
  }
}

Security Findings (24)

  • HighAS-002

    ⚠️Excessive Permissions ×8

    tool declares network permission

    get_open_targets_graphql_schemasearch_entitiesquery_open_targets_graphqlbatch_query_open_targets_graphql

    tool declares exec permission

    get_open_targets_graphql_schemasearch_entitiesquery_open_targets_graphqlbatch_query_open_targets_graphql

    Fix: Tool requests broad permissions (exec/fs/network). Validate input parameters using Enums where possible, and restrict file system operations to explicit allowed directories.

  • HighAS-003

    🔀Scope Mismatch ×2

    tool name "get_open_targets_graphql_schema" implies read-only operation but declares exec permission

    get_open_targets_graphql_schema

    tool name "search_entities" implies read-only operation but declares exec permission

    search_entities

    Fix: Ensure tool names, descriptions, and permission declarations are internally consistent. Use explicit naming conventions that fully reflect actual capabilities.

  • MediumAS-002

    ⚠️Excessive Permissions ×5

    tool declares fs permission

    get_open_targets_graphql_schema

    tool declares db permission

    get_open_targets_graphql_schemasearch_entitiesquery_open_targets_graphqlbatch_query_open_targets_graphql

    Fix: Tool requests broad permissions (exec/fs/network). Validate input parameters using Enums where possible, and restrict file system operations to explicit allowed directories.

  • LowAS-011

    ℹ️Missing Rate-Limit / Timeout ×4

    tool performs network or execution operations but declares no rate-limit, timeout, or retry configuration

    get_open_targets_graphql_schemasearch_entitiesquery_open_targets_graphqlbatch_query_open_targets_graphql

    Fix: Declare explicit rate-limit, timeout, and retry configuration for all network and execution tools. Implement exponential back-off and surface resource state to the calling agent.

  • InfoAS-014

    ℹ️Dependency Inventory Unavailable ×5

    Tool did not expose metadata.dependencies or repo_url, so supply-chain coverage is limited.

    get_open_targets_graphql_schemaget_type_dependenciessearch_entitiesquery_open_targets_graphqlbatch_query_open_targets_graphql

    Fix: Review and remediate the identified issue.

Scan this tool yourself

Reproduce this audit locally, integrate into CI, or let your agent audit its own tools.

Install once, then scan any MCP server:

$ curl -sfL https://raw.githubusercontent.com/AgentSafe-AI/tooltrust-scanner/main/install.sh | bash
$ tooltrust-scanner scan --server "npx -y opentargets"

Adjust the package name if your npm registry name differs from the tool ID. View source

Add badge to your README

Copy this Markdown to show your ToolTrust grade on GitHub.

[![ToolTrust Grade D](https://raw.githubusercontent.com/AgentSafe-AI/tooltrust-directory/main/docs/badges/grade-d.svg)](https://github.com/AgentSafe-AI/tooltrust-directory)